Time: 21:25 UTC+0, Sunday, November 30, 2025
Venue: Acrisure Stadium, Pittsburgh
In a classic AFC showdown with major playoff implications, the Buffalo Bills travel to face the Pittsburgh Steelers. The Bills’ explosive offense, orchestrated by Josh Allen, will be tested by the Steelers’ traditionally stout and physical defense. This interconference duel promises to be a compelling clash of styles, pitting Pittsburgh’s defensive discipline against Buffalo’s big-play capability. With both teams likely jockeying for postseason positioning, this late-November matchup is poised to deliver high-stakes, intense football from the opening kickoff.